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What's an NPI ?

These are methods targeted at a known health issue in Western medicine that are EXPLICABLE, EFFECTIVE, SAFE, and SUPERVISED by trained professionals. These physical, nutritional, and psychosocial practices complement other health solutions...

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The NPIS Registry: why ?

The NPIS Model standardized scientific framework is used to identify NPI that are explainable, effective, safe and reproducible, based on published studies. An independent, rigorous assessment process coordinated by the scientifc society NPIS and verifiable by all health authorities...

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Who is this platform for?

I am a citizen, a patient, a caregiver or a professional on a first visit

I will be able to easily find information on interventions that are actually INMs. I will also be able to provide feedback on usage. If I want to go further, I will be directed to the conditions for accessing all the data and features of the INM Repository.


I am a healthcare professional wishing to access all INM files

I will be able to find complete information on INM protocols to deepen my knowledge and practices. I will be able to provide feedback on use.


I am a representative of an authority, institution or organization related to health

If my practice organization is a partner of the NPIS, I will be able to access all the data and functionalities of the INM Repository.


I would like to submit a proposal for a new INM in the Repository

If my project meets the definition of an INM and if it is sufficiently supported by scientifically conducted studies, I will be directed to a form which will allow me to write the INM file relating to my project.


I am an expert selected under the INM file validation procedure

If I have received an email from NPIS accrediting me as an Expert in a defined field, I will be able to register to participate in the expert procedure for which I have been requested.


Become a Submitter

We are calling for applications to submit NPI sheets: Cliquez ici

Learn more about NPIS and NPI :

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NPIS Questions and Answers

Why an international scientific society for NPI ?
NPI are a field in which many amalgamations occur between scientific knowledge and opinion, due to their objective—human health—and their operational mode, which involves immaterial protocols. However, it is essential to learn to distinguish science from research amidst the multiplication of tools and information channels (Klein, 2020), particularly on the subject of NPI. The same communication channels transmit both scientific knowledge and beliefs, opinions, comments... Information of different statuses becomes intertwined. Knowledge can turn into the belief of a particular community, and vice versa.

Research, on the other hand, pertains to questions for which we do not yet have answers. These well-defined questions still have no answer. A researcher works on the subject using various methods and strategies. Research fosters doubt. Scientific societies work to advance research within a specific territory and theme.

Given that NPI are universal health protocols centered on individuals and administered by humans, an international multidisciplinary scientific society needed to be created. This has been achieved since 2021. This society is called the Non-Pharmacological Intervention Society (NPIS).
Why is the term NPI so little known?

The term NPI has been used by scientists working in the health field since 1975. However, it is not the only term; other similar terms are used synonymously, especially in PubMed. There are ten English terms to describe non-pharmacological processes and twenty-eight to describe methods of operation. An exhaustive inventory of NPI on a scientific article search engine is currently impossible due to the variety of terms researchers use, each with distinct meanings: rehabilitation intervention, psychosocial intervention, mental intervention, cognitive intervention, psychological intervention, behavioral intervention, psychosomatic intervention, nutrition intervention, dietary intervention, food intervention, physical intervention, body intervention, exercise intervention, manual intervention, salutogenic intervention, natural intervention, self-help intervention, nursing intervention, therapy intervention, care intervention, disease management intervention, multimodal intervention...

A search on PubMed from August 15, 2024, indicates 55,689 articles citing the term "non-pharmacological" or its equivalent up to 2023. While these figures do not challenge the trend, they are likely underestimated due to the database's focus on health products rather than services, biological treatments over psychosocial ones, studies on North American populations, and journals published by North American organizations. This aligns with an official U.S. government site managed by the National Center for Biotechnology Information and hosted by the National Library of Medicine, part of the National Institutes of Health (NIH).

A search on PubMed from August 15, 2024, also reveals 11,642 articles citing the term "non-pharmacological intervention" or its equivalent up to 2023. Both curves demonstrate an increase since 2000, with a notable acceleration since 2010.

The French National Authority for Health has been encouraging the use of the term NPI in health since 2011.

What is an evidence-based data point for an NPI?
An evidence-based data point is a theoretical or practical knowledge acquired through rigorous and integrated scientific methods and reasoning. The NPIS Model follows this logic in the health field (see Figure 3). It provides specific methodological and ethical recommendations for NPI for studies focusing on their mechanisms and explanatory processes (mechanistic study), their content (prototypical study), their evolution over time (observational study), their benefits and risks (interventional study), and their application and personalization modalities (implementation study).

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